Ionizing radiation enhances IL-6 and IL-8 production by human endothelial cells
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چکیده
منابع مشابه
Ionizing radiation enhances IL-6 and IL-8 production by human endothelial cells
Irradiation exposure is known to induce an inflammatory reaction. Endothelial cells play a crucial role both in the inflammatory process and in radiation damage. Therefore, supernatants and cell lysates of (60)Co-irradiated human umbilical vein endothelial cells (HUVEC) have been assessed for the presence of pro-inflammatory cytokines. After gamma irradiation, interleukin (IL)-1alpha, IL-1beta ...
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We and others have demonstrated previously the occurrence of cC1qR/CaR, a receptor for the collagen-like stalks of complement component C1q, on endothelial cells. In the present study we investigated whether binding of C1q to endothelial cells resulted in enhancement of cytokine or chemokine production. HUVEC produced 82 +/- 91 pg/ml of IL-8, 79 +/- 113 pg/ml of IL-6, and 503 +/- 221 pg/ml of m...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 1997
ISSN: 0962-9351,1466-1861
DOI: 10.1080/09629359791677